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Lgd-4033 5mg
LGD-4033 boasts high selectivity when it bonds to androgen-receptive cells in the body, opting for those in muscles and bonesas opposed to fat and hair.
When the team stimulated cells taken from the skin of these mice with testosterone and then treated them with a drug that blocks the effects of testosterone-blocking therapies, their testes shrank significantly and the mice lost all their fat, lgd-4033 5mg.
The next target is the prostate gland, but that is unlikely to be easy to develop, lgd-4033 5mg.
"It is a very tricky process of treating cells from the surface with testosterone and targeting the prostate gland," says Dr T.S. Kapoor, one of the study's three co-authors.
One option would be to build a transgenic mouse in which the gene for prostate cancer is turned off or reprogrammed, as is possible in other cancers, bulking in ramadan. Dr Kapoor, a specialist in genetic engineering, says many such efforts are on life-support at his lab.
Another hope would be to grow large numbers of these cells in an animal model, a process called xenotransplantation, which would likely take about 5 years. But there is little chance of this: "We do not have a gene therapy for prostate cancer," says Dr Kapoor.
So, the next phase in the quest for a treatment is to find ways to stop an unwanted cell spreading, such as a tumour that breaks out.
A more permanent, but still uncertain, solution would be to replace lost fat with new muscle tissue, dianabol buy usa.
"There are a lot of ways from a molecular point of view for the brain to regenerate into muscle," says Dr Kapoor, sarm cardarine 10 mg.
The research was supported by grants from the American Institute for Cancer Research (AI-163723, AI-163725, AI-163726). Research publications are available from The Scientist, at www.sciencedirect.com/science.
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